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BMCBI
2004
111views more  BMCBI 2004»
15 years 6 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
BMCBI
2004
124views more  BMCBI 2004»
15 years 6 months ago
XHM: A system for detection of potential cross hybridizations in DNA microarrays
Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be...
Kristian Flikka, Fekadu Yadetie, Astrid Lægr...
BMCBI
2004
131views more  BMCBI 2004»
15 years 6 months ago
A web services choreography scenario for interoperating bioinformatics applications
Background: Very often genome-wide data analysis requires the interoperation of multiple databases and analytic tools. A large number of genome databases and bioinformatics applic...
Remko de Knikker, Youjun Guo, Jin-long Li, Albert ...
BMCBI
2004
106views more  BMCBI 2004»
15 years 6 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
BMCBI
2004
228views more  BMCBI 2004»
15 years 6 months ago
An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
Romesh Stanislaus, Liu Hong Jiang, Martha Swartz, ...