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159
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ANOR
2011
15 years 1 months ago
2011
Hard problems for metaheuristic search can be a source of insight for developing better methods. We examine a challenging instance of such a problem that has exactly two local opt...
195
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BMCBI
2011
15 years 1 months ago
2011
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
165
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BMCBI
2011
15 years 1 months ago
2011
Background: Building repositories of computational models of biological systems ensures that published models are available for both education and further research, and can provid...
184
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BMCBI
2011
15 years 1 months ago
2011
Background: The identification of binding targets for proteins using ChIP-Seq has gained popularity as an alternative to ChIP-chip. Sequencing can, in principle, eliminate artifac...
216
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BMCBI
2011
15 years 1 months ago
2011
Background: DNA microarrays have become a nearly ubiquitous tool for the study of human disease, and nowhere is this more true than in cancer. With hundreds of studies and thousan...