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BMCBI
2004
94views more  BMCBI 2004»
15 years 6 months ago
The tissue microarray data exchange specification: implementation by the Cooperative Prostate Cancer Tissue Resource
Background: Tissue Microarrays (TMAs) have emerged as a powerful tool for examining the distribution of marker molecules in hundreds of different tissues displayed on a single sli...
Jules J. Berman, Milton Datta, Andre Kajdacsy-Ball...
BMCBI
2004
114views more  BMCBI 2004»
15 years 6 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2004
196views more  BMCBI 2004»
15 years 6 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
BMCBI
2004
176views more  BMCBI 2004»
15 years 6 months ago
Boosting accuracy of automated classification of fluorescence microscope images for location proteomics
Background: Detailed knowledge of the subcellular location of each expressed protein is critical to a full understanding of its function. Fluorescence microscopy, in combination w...
Kai Huang, Robert F. Murphy
BMCBI
2004
97views more  BMCBI 2004»
15 years 6 months ago
Performance of a genetic algorithm for mass spectrometry proteomics
Background: Recently, mass spectrometry data have been mined using a genetic algorithm to produce discriminatory models that distinguish healthy individuals from those with cancer...
Neal O. Jeffries