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BMCBI
2007
126views more  BMCBI 2007»
15 years 6 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
BMCBI
2007
141views more  BMCBI 2007»
15 years 6 months ago
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...
BMCBI
2007
155views more  BMCBI 2007»
15 years 6 months ago
ProMEX: a mass spectral reference database for proteins and protein phosphorylation sites
Background: In the last decade, techniques were established for the large scale genome-wide analysis of proteins, RNA, and metabolites, and database solutions have been developed ...
Jan Hummel, Michaela Niemann, Stefanie Wienkoop, W...
BMCBI
2007
169views more  BMCBI 2007»
15 years 6 months ago
The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats
Background: In Archeae and Bacteria, the repeated elements called CRISPRs for "clustered regularly interspaced short palindromic repeats" are believed to participate in ...
Ibtissem Grissa, Gilles Vergnaud, Christine Pource...
BMCBI
2007
125views more  BMCBI 2007»
15 years 6 months ago
Identification of discriminative characteristics for clusters from biologic data with InforBIO software
Background: There are a number of different methods for generation of trees and algorithms for phylogenetic analysis in the study of bacterial taxonomy. Genotypic information, suc...
Naoto Tanaka, Masataka Uchino, Satoru Miyazaki, Hi...