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150
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BMCBI
2008
15 years 6 months ago
2008
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
177
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BMCBI
2007
15 years 6 months ago
2007
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
182
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BMCBI
2008
15 years 6 months ago
2008
Background: Accurate peptide identification is important to high-throughput proteomics analyses that use mass spectrometry. Search programs compare fragmentation spectra (MS/MS) o...
135
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BMCBI
2007
15 years 6 months ago
2007
Background: G Protein-Coupled Receptors (GPCRs) are a large and diverse family of membrane proteins whose members participate in the regulation of most cellular and physiological ...
165
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BMCBI
2007
15 years 6 months ago
2007
Background: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which...