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» A Probabilistic Identification Result
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BMCBI
2010
97views more  BMCBI 2010»
15 years 7 months ago
Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembr
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
Shu-An Chen, Tzong-Yi Lee, Yu-Yen Ou
BMCBI
2007
99views more  BMCBI 2007»
15 years 7 months ago
RepSeq - A database of amino acid repeats present in lower eukaryotic pathogens
Background: Amino acid repeat-containing proteins have a broad range of functions and their identification is of relevance to many experimental biologists. In human-infective prot...
Daniel P. Depledge, Ryan P. J. Lower, Deborah F. S...
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BMCBI
2008
99views more  BMCBI 2008»
15 years 7 months ago
NestedMICA as an ab initio protein motif discovery tool
Background: Discovering overrepresented patterns in amino acid sequences is an important step in protein functional element identification. We adapted and extended NestedMICA, an ...
Mutlu Dogruel, Thomas A. Down, Tim J. P. Hubbard
BMCBI
2008
108views more  BMCBI 2008»
15 years 7 months ago
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
Background: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications...
David A. Nix, Samir J. Courdy, Kenneth M. Boucher
BMCBI
2008
74views more  BMCBI 2008»
15 years 7 months ago
Prediction of mucin-type O-glycosylation sites in mammalian proteins using the composition of k-spaced amino acid pairs
Background: As one of the most common protein post-translational modifications, glycosylation is involved in a variety of important biological processes. Computational identificat...
Yong-Zi Chen, Yu-Rong Tang, Zhi-Ya Sheng, Ziding Z...