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» A Perspective on Evolutionary Computation
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BMCBI
2006
159views more  BMCBI 2006»
15 years 7 months ago
EVEREST: automatic identification and classification of protein domains in all protein sequences
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
Elon Portugaly, Amir Harel, Nathan Linial, Michal ...
EC
2006
195views ECommerce» more  EC 2006»
15 years 6 months ago
Automated Global Structure Extraction for Effective Local Building Block Processing in XCS
Learning Classifier Systems (LCSs), such as the accuracy-based XCS, evolve distributed problem solutions represented by a population of rules. During evolution, features are speci...
Martin V. Butz, Martin Pelikan, Xavier Llorà...
BMCBI
2007
144views more  BMCBI 2007»
15 years 6 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
GPEM
2007
119views more  GPEM 2007»
15 years 6 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
NAR
2006
177views more  NAR 2006»
15 years 6 months ago
PUMA2 - grid-based high-throughput analysis of genomes and metabolic pathways
The PUMA2 system (available at http://compbio.mcs. 10 anl.gov/puma2) is an interactive, integrated bioinformatics environment for high-throughput genetic sequence analysis and met...
Natalia Maltsev, Elizabeth M. Glass, Dinanath Sula...