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» A Note on Difference Sets
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BMCBI
2007
200views more  BMCBI 2007»
15 years 6 months ago
Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
Ágnes Baross, Allen D. Delaney, H. Irene Li...
BMCBI
2006
104views more  BMCBI 2006»
15 years 6 months ago
SinicView: A visualization environment for comparisons of multiple nucleotide sequence alignment tools
Background: Deluged by the rate and complexity of completed genomic sequences, the need to align longer sequences becomes more urgent, and many more tools have thus been developed...
Arthur Chun-Chieh Shih, D. T. Lee, Laurent Lin, Ch...
BMCBI
2006
146views more  BMCBI 2006»
15 years 6 months ago
GeneTools - application for functional annotation and statistical hypothesis testing
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
Vidar Beisvag, Frode K. R. Jünge, Hallgeir Be...
BMCBI
2005
113views more  BMCBI 2005»
15 years 6 months ago
Microarray scanner calibration curves: characteristics and implications
Background: Microarray-based measurement of mRNA abundance assumes a linear relationship between the fluorescence intensity and the dye concentration. In reality, however, the cal...
Leming M. Shi, Weida Tong, Zhenqiang Su, Tao Han, ...
BMCBI
2002
89views more  BMCBI 2002»
15 years 6 months ago
Sources of variability and effect of experimental approach on expression profiling data interpretation
Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...
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