16518 search results - page 3073 / 3304 » A New Approach to Splitting-Off |
175
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BMCBI
2010
15 years 6 months ago
2010
Background: The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by ...
243
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BMCBI
2008
15 years 6 months ago
2008
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
190
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BMCBI
2010
15 years 6 months ago
2010
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
188
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BMCBI
2007
15 years 6 months ago
2007
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
177
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BMCBI
2007
15 years 6 months ago
2007
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...