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BMCBI
2010
112views more  BMCBI 2010»
15 years 6 months ago
Knowledge-based analysis of microarrays for the discovery of transcriptional regulation relationships
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
Junhee Seok, Amit Kaushal, Ronald W. Davis, Wenzho...
BMCBI
2010
112views more  BMCBI 2010»
15 years 6 months ago
The MetabolomeExpress Project: enabling web-based processing, analysis and transparent dissemination of GC/MS metabolomics datas
Background: Standardization of analytical approaches and reporting methods via community-wide collaboration can work synergistically with web-tool development to result in rapid c...
Adam J. Carroll, Murray R. Badger, A. Harvey Milla...
BMCBI
2008
140views more  BMCBI 2008»
15 years 6 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2008
115views more  BMCBI 2008»
15 years 6 months ago
Systems biology driven software design for the research enterprise
Background: In systems biology, and many other areas of research, there is a need for the interoperability of tools and data sources that were not originally designed to be integr...
John Boyle, Christopher C. Cavnor, Sarah A. Killco...
BMCBI
2010
133views more  BMCBI 2010»
15 years 6 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
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