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267
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NIPS
2008
15 years 8 months ago
Optimization on a Budget: A Reinforcement Learning Approach
Many popular optimization algorithms, like the Levenberg-Marquardt algorithm (LMA), use heuristic-based "controllers" that modulate the behavior of the optimizer during ...
Paul Ruvolo, Ian R. Fasel, Javier R. Movellan
203
Voted
BMCBI
2010
205views more  BMCBI 2010»
15 years 7 months ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
181
Voted
BMCBI
2008
130views more  BMCBI 2008»
15 years 7 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2006
93views more  BMCBI 2006»
15 years 7 months ago
A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database
Background: Many of the most popular pre-processing methods for Affymetrix expression arrays, such as RMA, gcRMA, and PLIER, simultaneously analyze data across a set of predetermi...
Simon Katz, Rafael A. Irizarry, Xue Lin, Mark Trip...
172
Voted
BMCBI
2007
103views more  BMCBI 2007»
15 years 6 months ago
Systems biology approach for mapping the response of human urothelial cells to infection by Enterococcus faecalis
Background: To better understand the response of urinary epithelial (urothelial) cells to Enterococcus faecalis, a uropathogen that exhibits resistance to multiple antibiotics, a ...
Mikhail G. Dozmorov, Kimberly D. Kyker, Ricardo Sa...