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BMCBI
2008
96views more  BMCBI 2008»
15 years 7 months ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
BMCBI
2007
110views more  BMCBI 2007»
15 years 7 months ago
Analysis of feedback loops and robustness in network evolution based on Boolean models
Background: Many biological networks such as protein-protein interaction networks, signaling networks, and metabolic networks have topological characteristics of a scale-free degr...
Yung-Keun Kwon, Kwang-Hyun Cho
BMCBI
2006
95views more  BMCBI 2006»
15 years 6 months ago
XcisClique: analysis of regulatory bicliques
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
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BMCBI
2007
147views more  BMCBI 2007»
15 years 6 months ago
Comparative analysis of long DNA sequences by per element information content using different contexts
Background: Features of a DNA sequence can be found by compressing the sequence under a suitable model; good compression implies low information content. Good DNA compression mode...
Trevor I. Dix, David R. Powell, Lloyd Allison, Jul...
BMCBI
2005
173views more  BMCBI 2005»
15 years 6 months ago
Phydbac "Gene Function Predictor" : a gene annotation tool based on genomic context analysis
Background: The large amount of completely sequenced genomes allows genomic context analysis to predict reliable functional associations between prokaryotic proteins. Major method...
François Enault, Karsten Suhre, Jean-Michel...