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BMCBI
2010
172views more  BMCBI 2010»
15 years 1 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
KDD
2003
ACM
133views Data Mining» more  KDD 2003»
16 years 7 months ago
Interactive Analysis of Gene Interactions Using Graphical gaussian model
DNA microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Xintao Wu, Yong Ye, Kalpathi R. Subramanian
ICDM
2009
IEEE
92views Data Mining» more  ICDM 2009»
15 years 4 months ago
Semi-supervised Multi-task Learning with Task Regularizations
Multi-task learning refers to the learning problem of performing inference by jointly considering multiple related tasks. There have already been many research efforts on supervise...
Fei Wang, Xin Wang, Tao Li
BMCBI
2007
130views more  BMCBI 2007»
15 years 7 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
TMI
2002
143views more  TMI 2002»
15 years 6 months ago
A Support Vector Machine Approach for Detection of Microcalcifications
In this paper, we investigate an approach based on support vector machines (SVMs) for detection of microcalcification (MC) clusters in digital mammograms, and propose a successive ...
Issam El-Naqa, Yongyi Yang, Miles N. Wernick, Niko...