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BMCBI
2010
185views more  BMCBI 2010»
15 years 6 months ago
ABCtoolbox: a versatile toolkit for approximate Bayesian computations
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...
BMCBI
2010
89views more  BMCBI 2010»
15 years 6 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
BMCBI
2007
95views more  BMCBI 2007»
15 years 6 months ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim
GECCO
2007
Springer
155views Optimization» more  GECCO 2007»
16 years 18 days ago
Observing the swarm behaviour during its evolutionary design
Evolutionary Algorithms (EAs) can be used for designing Particle Swarm Optimization (PSO) algorithms that work, in some cases, considerably better than the human-designed ones. By...
Laura Diosan, Mihai Oltean
APBC
2004
164views Bioinformatics» more  APBC 2004»
15 years 7 months ago
Cluster Ensemble and Its Applications in Gene Expression Analysis
Huge amount of gene expression data have been generated as a result of the human genomic project. Clustering has been used extensively in mining these gene expression data to find...
Xiaohua Hu, Illhoi Yoo