Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
Background: Methods of determining whether or not any particular HIV-1 sequence stems - completely or in part - from some unknown HIV-1 subtype are important for the design of vac...
Thomas Unterthiner, Anne-Kathrin Schultz, Jan Bull...
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
Hugues Sicotte, David N. Rider, Gregory A. Poland,...
We present a new algorithm for the problems of genotype phasing and block partitioning. Our algorithm is based on a new stochastic model, and on the novel concept of probabilistic...
We introduce the concept of "minimal" search algorithm for a set of functions to optimize. We investigate the structure of closed under permutation (c.u.p.) sets and we c...