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BMCBI
2007
15 years 6 months ago
2007
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
197
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BMCBI
2010
15 years 6 months ago
2010
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
193
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BMCBI
2007
15 years 6 months ago
2007
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
182
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BMCBI
2007
15 years 6 months ago
2007
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
186
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BMCBI
2008
15 years 6 months ago
2008
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...