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162
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BMCBI
2007
15 years 6 months ago
2007
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
188
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BMCBI
2008
15 years 6 months ago
2008
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
169
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BMCBI
2010
15 years 6 months ago
2010
Background: It is hypothesized that common, complex diseases may be due to complex interactions between genetic and environmental factors, which are difficult to detect in high-di...
177
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BMCBI
2007
15 years 6 months ago
2007
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
249
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BMCBI
2008
15 years 6 months ago
2008
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...