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» A Data Model for Effectively Computable Functions
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BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
BMCBI
2006
94views more  BMCBI 2006»
15 years 6 months ago
Simulation of microarray data with realistic characteristics
Background: Microarray technologies have become common tools in biological research. As a result, a need for effective computational methods for data analysis has emerged. Numerou...
Matti Nykter, Tommi Aho, Miika Ahdesmäki, Pek...
JCB
2007
130views more  JCB 2007»
15 years 6 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
TCAD
2008
114views more  TCAD 2008»
15 years 6 months ago
Test-Quality/Cost Optimization Using Output-Deviation-Based Reordering of Test Patterns
At-speed functional testing, delay testing, and n-detection test sets are being used today to detect deep submicrometer defects. However, the resulting test data volumes are too hi...
Zhanglei Wang, Krishnendu Chakrabarty
PAMI
2011
15 years 1 months ago
Approximately Global Optimization for Robust Alignment of Generalized Shapes
—In this paper, we introduce a novel method to solve shape alignment problems. We use gray-scale “images” to represent source shapes, and propose a novel two-component Gaussi...
Hongsheng Li, Tian Shen, Xiaolei Huang