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BMCBI
2008
124views more  BMCBI 2008»
15 years 6 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2008
134views more  BMCBI 2008»
15 years 6 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
DEBU
2010
88views more  DEBU 2010»
15 years 6 months ago
SECONDO: A Platform for Moving Objects Database Research and for Publishing and Integrating Research Implementations
Databases supporting time dependent and continuously changing geometries, called moving objects databases, have been studied for about 15 years. The field has been flourishing and...
Ralf Hartmut Güting, Thomas Behr, Christian D...
BMCBI
2006
81views more  BMCBI 2006»
15 years 6 months ago
Multipolar representation of protein structure
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
Apostol Gramada, Philip E. Bourne
BMCBI
2006
203views more  BMCBI 2006»
15 years 6 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...