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BMCBI
2008
138views more  BMCBI 2008»
15 years 6 months ago
Information transfer in signaling pathways: A study using coupled simulated and experimental data
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown. Since quite divers...
Jürgen Pahle, Anne K. Green, C. Jane Dixon, U...
BMCBI
2010
122views more  BMCBI 2010»
15 years 6 months ago
Fast and accurate protein substructure searching with simulated annealing and GPUs
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
Alex Stivala, Peter J. Stuckey, Anthony Wirth
BMCBI
2008
146views more  BMCBI 2008»
15 years 6 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
IIE
2007
116views more  IIE 2007»
15 years 6 months ago
Turtle's Navigation and Manipulation of Geometrical Figures Constructed by Variable Processes in a 3d Simulated Space
Abstract. Issues related to 3d turtle’s navigation and geometrical figures’ manipulation in the simulated 3d space of a newly developed computational environment, MaLT, are re...
Chronis Kynigos, Maria Latsi
MMAS
2011
Springer
15 years 1 months ago
Scalable Bayesian Reduced-Order Models for Simulating High-Dimensional Multiscale Dynamical Systems
While existing mathematical descriptions can accurately account for phenomena at microscopic scales (e.g. molecular dynamics), these are often high-dimensional, stochastic and thei...
Phaedon-Stelios Koutsourelakis, Elias Bilionis