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» A Calculus for Data Mapping
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BMCBI
2006
151views more  BMCBI 2006»
15 years 7 months ago
Modeling Sage data with a truncated gamma-Poisson model
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2005
147views more  BMCBI 2005»
15 years 6 months ago
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
JCB
2007
130views more  JCB 2007»
15 years 6 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2011
14 years 10 months ago
PeakRanger: A cloud-enabled peak caller for ChIP-seq data
Background: Chromatin immunoprecipitation (ChIP), coupled with massively parallel short-read sequencing (seq) is used to probe chromatin dynamics. Although there are many algorith...
Xin Feng, Robert Grossman, Lincoln Stein
SIGMOD
2009
ACM
136views Database» more  SIGMOD 2009»
16 years 7 months ago
A comparison of approaches to large-scale data analysis
There is currently considerable enthusiasm around the MapReduce (MR) paradigm for large-scale data analysis [17]. Although the basic control flow of this framework has existed in ...
Andrew Pavlo, Erik Paulson, Alexander Rasin, Danie...